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外観
白色～わずかにうすい褐色, 結晶
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溶解性
エタノールに溶けやすく、水に溶けにくい。
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用途
有機合成原料。
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用途
ベンズイミダゾール系殺菌剤の分析、研究用。
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化学的特性
Light yellow to cream or beige powder or flakes. N,N'-o-Phenyleneguanidine [934-32-7], 2-aminobenzimidazole, C7H7N3, Mr 133.15, mp 231 – 232 ℃(decomp.), obtained by cyclization of o-phenylenediamine with cyanogen chloride or cyanamide, is the nucleus for a number of compounds of economic interest.
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定義
ChEBI: 2-aminobenzimidazole is a member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. It has a role as a marine xenobiotic metabolite.
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製造方法
Synthesis of 2-aminobenzimidazole: Cyanogen bromide (3.5 g., 0.034 mole) was added in small portions, with shaking, to a suspension of o-phenylenediamine (4.2 g. , 0.34 mole) in water (40 ml), the exothermic reaction mixture was cooled to room temperature and it was stirred for 36hrs. The solution was filtered after standing overnight. Sodium hydroxide (1.4 g., 0.034 mole) in 30 ml of water was then added and the solution was evaporated. The solid thus obtained was filtered and recrystalized from water. Yield 85%, m.p. 228 - 230°C
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一般的な説明
Plates (in water); white powder.
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空気と水の反応
Insoluble in water.
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反応プロフィール
2-Aminobenzimidazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.
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健康ハザード
ACUTE/CHRONIC HAZARDS: When heated to decomposition 2-Aminobenzimidazole emits toxic fumes of nitrogen oxides.
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火災危険
Flash point data for 2-Aminobenzimidazole are not available; however, 2-Aminobenzimidazole is probably combustible.
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安全性プロファイル
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic NO,. See also AROUTIC AMINES.
