トリクロロメチアジド

外観

白色～ほとんど白色粉末～結晶

効能

血圧降下薬, 利尿薬, Na+-Cl-再吸収阻害薬

商品名

フルイトラン (塩野義製薬)

化学的特性

Trichlormethiazide occurs as a white or practically white, crystalline powder and may have a slight characteristic odor.

使用

Trichlormethiazide is a diuretic and anti-hypertensive agent from the benzothiadiazide class which is used in veterinary medicine in cattle, sheep, goats, pigs and horses, at the following therapeutic regimen: a single intramuscular dose of 0.4 mg/kg bw followed by two oral doses of 0.8 mg/kg bw given 12 and 36 hours after the first administration.
Trichlormethiazide is also used in humans in the United States as a diuretic and anti-hypertensive substance but not in the European Union. The usual dose is 2 to 4 mg twice a day (i.e. approximately 0.033 to 0.066 mg/kg bw/day).