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Tacrolimus Monohydrate Structure

Tacrolimus Monohydrate

Chemical Properties

Melting point 127-129°
alpha  D23 -84.4° (c = 1.02 in chloroform)
storage temp.  -20°C
solubility  DMSO: soluble20mg/mL
form  powder
color  White to Almost white
Merck  14,9025
InChIKey NWJQLQGQZSIBAF-MLAUYUEBSA-N

Safety Information

Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  KD4201200
HazardClass  6.1
PackingGroup  III
HS Code  2934990002
Toxicity LD50 i.p. in mice: >200 mg/kg (Kino); LD50 in male, female rats (mg/kg): 57.0, 23.6 i.v.; 134, 194 orally (Ohara)

Usage And Synthesis

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