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外観
無色～わずかにうすい黄色, 澄明の液体
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溶解性
エタノール及びアセトンに混和するが、水に溶けにくい。溶解度:0.53g/100g 水、20℃。エタノール及びアセトンに極めて溶けやすく、水に溶けにくい。
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用途
溶剤。有機合成原料。
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用途
天然樹脂、合成樹脂の溶剤、香味料
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説明
4-Heptanone has a penetrating odor and burning taste. It is prepared by passing butyric acid over a wood coal at 425°C and then
over cerium oxide at 500°C or over thorium oxide; also over
manganese oxide at 400 - 425°C.
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化学的特性
4-Heptanone has a penetrating odor and burning taste.
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天然物の起源
Reported found in apple juice, papaya, pear, cabbage, baked potato, roasted peanut, chicken fat, coffee, bachang (Mangifera foetida L ) and rooibus tea (Aspalathius linearis)
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使用
4-Heptanone is used as a solvent for nitrocellulose as well as in organic synthesis. It is involved in the preparation of flavorings. It is used as an intermediate in the synthesis of active pharmaceutical ingredients. Further, it is used in paints and coatings.
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製造方法
By passing butyric acid over wood coal at 425°C and then over cerium oxide at 500°C or over thorium oxide; also over manganese oxide at 400 to 425°C.
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一般的な説明
A colorless liquid with a pleasant odor. Insoluble in water and less dense than water. Flash point 120°F. Toxic by inhalation. A skin irritant. Used to make flavorings and as a solvent.
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空気と水の反応
Flammable. Insoluble in water.
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反応プロフィール
4-Heptanone is incompatible with the following: Oxidizers .
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健康ハザード
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
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火災危険
Combustible liquid; flash point (closed cup)
49°C (120°F); vapor density 3.9 (air = 1);
vapor pressure 5.2 torr at 20°C (68°F); fireextinguishing agent: “alcohol” foam or water
spray. DPK forms explosive mixtures with
air; LEL and UEL values have not been
reported. It is incompatible with strong acids,
alkalies, and oxidizers.
.
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安全性プロファイル
and skin contact. A
skin and eye irritant. Flammable liquid when
exposed to heat or flame; can react with
oxidizing materials. To fight fire, use CO2,
dry chemical, alcohol foam, fog, and mist.
When heated to decomposition it emitsacrid smoke and fumes. See also
KETONES.
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代謝
When 950 mg methyl amyl ketone/kg body weight was administered orally to rabbits, 40% was excreted as heptyl-2-glucuronide, and traces of the unchanged ketone were also found in the urine (Kamil, Smith & Williams, 1953). 2-Heptanone (methyl amyl ketone) was identified as being among the approximately 300 compounds present in the volatile constituents of urine from male and female subjects (Zlatkis & Liebich, 1971).
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純化方法
Dry 4-pentanone with CaSO4, then distil it from P2O5 under nitrogen. [Beilstein 1 IV 3323.]
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廃棄物の処理
DPK is burned in a chemical incineratorequipped with an afterburner and scrubber.
