スダン ＩＩＩ

外観

暗赤褐色の粉末

定義

本品は、平成15年厚労省令第126号に示される赤色225号である。

溶解性

クロロホルム，キシレン，酢酸に可溶。エタノール，エーテル，アセトンに難溶。水に不溶。クロロホルム溶状 : 本品 0.1g)+クロロホルム(→20ml)。アセトン及びクロロホルムに溶け、水及びエタノールにほとんど溶けない。

用途

クロマトグラフィー(液体、薄層)における標準。活性アルミナの活性度検定用。

用途

高速液体クロマトグラフ法によるズダン3定量用標準品。

用途

中性脂肪の染色、活性アルミナの活性度検定、非水滴定指示薬。

用途

酢酸中での酸塩基滴定(非水滴定)における指示薬(塩基性色:黄色、酸性色:赤)。活性アルミナの活性度検定用。

化粧品の成分用途

着色剤

説明

Solvent Red 23 is an oil-soluble red azo dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD and to paminoazobenzene. One case of contact dermatitis was reported in the metal industry.

化学的特性

reddish brown powder

定義

ChEBI: A bis(azo) compound that is 2-naphthol substituted at position 1 by a 4-{[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound l pids in paraffin sections.

製造方法

4-(Phenyldiazenyl)benzenamine diazotization, and Naphthalen-2-ol coupling. Note: some goods by 4-(Phenyldiazenyl)benzenamine and 2-Methyl-4-(o-tolyldiazenyl)benzenamine mixture as diazo components and have to.

接触アレルゲン

Solvent Red 23 is an oil-soluble red azo-dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD (the molecule is likely to be hydrolyzed into PPD) and to p-aminoazobenzene. One case of contact dermatitis was reported in the metal industry.

安全性プロファイル

Poison by intraperitoneal route. Moderately toxic by subcutaneous and intrapleural routes. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

純化方法

Crystallise the dye from EtOH, EtOH/water or *benzene/absolute EtOH (1:1). [Beilstein 16 II 75, 16 III 148, 16 IV 248.]