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外観
白色〜わずかにうすい赤色又はわずかにうすい褐色, 結晶〜結晶性粉末又はフレーク又は塊
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定義
本品は、次の化学式で表される有機化合物である。
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溶解性
エタノールに溶けやすい。
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解説
4-ヘキシルレソルシノール,淡黄色の針状晶．融点68～70 ℃，沸点178～180 ℃(1 kPa)．刺激臭と収れん性の味をもつ．エタノール，エーテル，ベンゼンなどに易溶，水に難溶．粘膜を強く刺激し，回虫や十二指腸虫の駆除に用いられるが，繰り返しの使用は注意が必要である．
森北出版「化学辞典（第2版）
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用途
殺菌・消毒剤。駆虫薬原料。有機合成原料。
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化粧品の成分用途
抗菌剤、口腔衛生剤、殺菌剤、酸化防止剤
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効能
駆虫薬, 消毒薬
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製造
4-ヘキシルレソルシノール,レソルシノールとヘキサン酸とを縮合させ，ついでカルボニル基を還元してつくられる．
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化学的特性
slightly red powder
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製造方法
The preparation of 4-Hexylresorcinol involves two methods:
The reaction of caproic acid and resorcinol in the presence of a catalyst.
Reduction of hexanoylresorcinol with zinc amalgam and dilute hydrochloric acid.
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一般的な説明
P-hexylresorcinol appears as pale-yellow viscous liquid (that becomes solid on standing at room temperature) or a peach colored powder. Pungent faintly fatty odor. Sharp astringent taste. (NTP, 1992)
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空気と水の反応
Insoluble in water.
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反応プロフィール
4-Hexyl-1,3-benzenediol may be sensitive to prolonged exposure to light. Incompatible with acid chlorides, acid anhydrides and oxidizing agents .
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危険性
Irritant to respiratory tract and skin, concentrated solutions are vesicant.
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火災危険
Flash point data for 4-Hexyl-1,3-benzenediol are not available. 4-Hexyl-1,3-benzenediol is probably combustible.
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臨床応用
Hexylresorcinol, also known as 4-hexylresorcinol, is a white crystalline substance with a faint phenolic odor. When applied to the tongue it produces a sensation of numbness. It is freely soluble in alcohol but only slightly soluble in water(1–20,000 parts). Hexylresorcinol is an effective antiseptic,possessing both bactericidal and fungicidal properties.The phenol coefficient of hexylresorcinol against S. aureusis 98. As is typical for alkylated phenols, hexylresorcinol possesses surfactant properties. The compound also haslocal anesthetic activity. Hexylresorcinol is formulated into throat lozenges because of its local anesthetic and antisepticproperties. These preparations are probably of little value. Hexylresorcinol (in the concentration in thelozenge) is probably not antiseptic, and the local anestheticproperty can anesthetize the larynx, causing temporary laryngitis.
