延命草素 性质
| 熔点 | 274-276℃ (Decomposition) (ethanol ) |
|---|---|
| 沸点 | 610.3±55.0 °C(Predicted) |
| 密度 | 1.37±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 12.66±0.60(Predicted) |
延命草素 用途与合成方法
Enmein 从 I. serra 中分离，具有免疫抑制作用。
Enmein shows significant inhibitory effect toward K562 with an IC 50 value ranging from 3.2 μg/ml to 8.2 μg/ml. Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml. Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%.
Cell Viability Assay
| Cell Line: | Splenic lymphocyte cells |
| Concentration: | 3.13, 6.25, 12.5, 25 μg/ml |
| Incubation Time: | 48 hours |
| Result: | Exhibited an IC 50 value of 17 μg/ml in splenic lymphocytes. |
Cell Cycle Analysis
| Cell Line: | Splenic lymphocyte cells |
| Concentration: | 5.5 μg/ml, 11 μg/ml, 22 μg/ml |
| Incubation Time: | 48 hours |
| Result: | Caused S stage cells and G2/M stage cells decreased. |
Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression.
| Animal Model: | Balb/c mice |
| Dosage: | 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg |
| Administration: | Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days |
| Result: | Had inhibitory effect on IL-2 release in blood. |
化学性质
白色针状色结晶，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于溪黄草。 延命草素供应商 更多
湖州展舒生物科技有限公司
黄金产品
联系电话：0572-8889530 18167260939
产品介绍：
云南西力生物技术股份有限公司
联系电话：0871-65217109 13211707573;
产品介绍：
中文名称：延命素
英文名称：Enmein
CAS：3776-39-4
纯度：98.0%
包装信息：5mg
备注：BBP03555
上海同田生物技术有限公司
联系电话：021-51320588
产品介绍：
中文名称：延命草素
英文名称：Enmein
CAS：3776-39-4
纯度：more than 98% HPLC
包装信息：10mg;20mg;1g;10g;100g standard packing or according to customers' requirement
成都瑞芬思德丹生物科技有限公司
联系电话：18302802153 18981717076
产品介绍：
中文名称：延命草素
英文名称：Enmein
CAS：3776-39-4
纯度：98% HPLC
包装信息：20Mg;100Mg;500Mg;1g;10g;kg
备注：标准品
