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外観
黄褐色〜赤褐色, 結晶性粉末〜粉末
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定義
本品は、トウモロコシ Zea mays から得られるアルコール可溶性タンパクである。
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溶解性
エタノールに溶け、水に溶けにくい。
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用途
医薬品原料(コーティング剤, 結合剤, 滑沢剤, 酸化防止剤), プラスチック等研究用。
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用途
コーティング剤、抗酸化剤、ゲル化剤。
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化粧品の成分用途
ヘアコンディショニング剤、皮膚コンディショニング剤、皮膜形成剤
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化学的特性
Zein is a prolamin obtained from corn (Zea mays Linne' (Fam.
Gramineae)). It occurs as a granular, straw- to pale yellow-colored
amorphous powder or fine flakes and has a characteristic odor and
bland taste.
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使用
Zein is a corn protein produced from corn gluten meal. it lacks the
amino acids, lysine and tryptophan, so it is not suitable as a sole
source of dietary protein. it is insoluble in water and alcohols but is
soluble in aqueous alcohols, glycols, and glycol ethers. it functions
as a film and coating to provide a moisture barrier for nuts and grain
products. it also functions as a coating for confections and a glaze
for panned goods.
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調製方法
Zein is extracted from corn gluten meal with dilute propan-2-ol.
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一般的な説明
Zein is a prolamine and an alcohol soluble protein present in maize endosperm cells. Zein is a 20kDa structural protein and is encoded by the gene mapped on the short arm of maize chromosome 7. This protein lacks essential amino acids, such as lysine and tryptophan. Therefore, it has a poor nutritional value.
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応用例（製薬）
Zein is used as a tablet binder in wet-granulation processes or as a
tablet-coating agent mainly as a replacement for shellac. It is used
primarily as an enteric-coating agent or in extended-release oral
tablet formulations and other delivery systems. Zein is also used
in food applications as a coating agent.
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安全性プロファイル
When heated to
decomposition it emits acrid smoke and
irritating fumes.
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安全性
Zein is used in oral pharmaceutical formulations and food
products, and is generally regarded as an essentially nontoxic and
nonirritant material at the levels employed as an excipient.
However, it may be harmful if ingested in large quantities.
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貯蔵
Zein should be stored in an airtight container, in a cool, dry place. It
has not been reported to polymerize.
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不和合性
Incompatible with oxidizing agents.
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規制状況(Regulatory Status)
GRAS listed. Included in the FDA Inactive Ingredients Database
(oral tablets). Included in nonparenteral medicines licensed in the
UK. Included in the Canadian List of Acceptable Non-medicinal
Ingredients.
