ピペラシリンナトリウム

外観

白色粉末～結晶

効能

抗生物質, 細胞壁合成阻害薬

商品名

ピペラシリンNa (ケミックス); ピペラシリンNa (東和薬品); ピペラシリンNa (武田テバファーマ); ピペラシリンNa (沢井製薬); ピペラシリンナトリウム (ニプロ); ペントシリン (富士フイルム富山化学); ペントシリン (富士フイルム富山化学)

説明

Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.

化学的特性

White to off-white crystalline powder

使用

A broad spectrum antibiotic targeting a wide range of susceptible gram positive and gram negative bacteria. Piperacillin sodium salt is an antibiotic. It is used in pharmacokinetic studies to optimize antimicrobial therapy and in hypersensitivity reactions. It is involved in the study of multidrug-resistant organisms. It acts as an antibiotic related to penicillin.

brand name

Pipracil (Wyeth).