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外観
白色～うすい黄色, 結晶～粉末
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溶解性
エタノール及びアセトンに極めて溶けやすく、水にほとんど溶けない。
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用途
持続性タンパク同化ステロイ
ド剤です。タンパク同化作用を示します。
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効能
タンパク同化薬, アンドロゲン受容体作動薬
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説明
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. The process for creating esters of [nandrolone] was patented in Spain in 1959 and in 1960, it was described as having a long duration of action and strong anabolic effect compared to nandrolone and other esters. Nandrolone decanoate was granted FDA approval on 5 October 1962.
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化学的特性
White or almost white, crystalline powder.
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使用
Nandrolone Decanoate is an anabolic steroid. Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women. Nandrolone Decanoate is also used for some aplastic anemias.
Control
led Substance.
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世界保健機関（WHO）
Nandrolone decanoate, an anabolic steroid, was introduced in
1962. In 1982, low dosage preparations were prohibited in Bangladesh due to
inadmissible promotion of products containing anabolic steroids for malnourished
children. Higher dosage preparations of nandrolone decanoate remain available in
many countries, including Bangladesh, for several highly specific but limited
indications that apply to patients with chronic debilitating and emaciating
diseases, particularly associated with neoplasia and some types of aplastic
anaemia.
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一般的な説明
Nandrolone decanoate,17β-hydroxyestr-4-en-3-one 17-decanoate, has been used inthe management of certain anemias, but the availability oferythropoietin has greatly reduced this use.
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Biochem/physiol Actions
Compared to testosterone propionate, nandrolone decanoate is considered to have strong anabolic effects but weak androgenic effects (potency ratios of 3.29–4.92 and 0.31–0.41). In particular, nandrolone esters are thought to have the highest ratio of anabolic to androgenic effects of any AAS. The low androgenicity of nandrolone decanoate is thought to be due to the fact that nandrolone is inactivated by 5α-reductase via transformation into the low-affinity androgen receptor (AR) ligand 5α-dihydronandrolone. This is thought to result in a lower incidence and magnitude of side effects.Nandrolone decanoate (ND) injection has been classified as a Schedule III controlled substance under the Anabolic Steroids Control Act of 1990. Due to serious health risks, the nonmedical use of AASs is banned by most sports organizations[1].
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安全性プロファイル
Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
