XL147

XL147 analog is an analog of XL147 .

XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases.

ChEBI: XL147 is a sulfonamide that is the N-4-toluenesulfonyl (N-tosyl) derivative of N-(2,1,3-benzothiadiazol-5-yl)quinoxaline-2,3-diamine. A selective PI3K inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an antineoplastic agent. It is a sulfonamide, a quinoxaline derivative, a benzothiadiazole and an aromatic amine.

PI3Kα