ピルビン酸メチル

化学名:ピルビン酸メチル

CAS番号.600-22-6

英語名:Methyl pyruvate

CBNumberCB8405108

MFC4H6O3

MW102.09

别名

ピルビン酸メチル

2-オキソプロパン酸メチル

trans-ピルビン酸メチル

ピルビン酸メチル物理性質

融点	-22 °C
沸点	134-137 °C (lit.)
比重(密度)	1.13 g/mL at 25 °C (lit.)
屈折率	n20/D 1.404(lit.)
闪点	103 °F
貯蔵温度	2-8°C
溶解性	エタノール：可溶1.1g/10mL 無色透明～ほぼ無色透明
外見	液体
色	黄ばみ
水溶解度	クロロホルム、メタノール、エーテル、アルコールに可溶。水にわずかに溶ける。
Merck	14,8021
BRN	1361953
LogP	-0.159 (est)
CAS データベース	600-22-6(CAS DataBase Reference)
NISTの化学物質情報	Propanoic acid, 2-oxo-, methyl ester(600-22-6)

安全性情報

危険有害性情報のコード(GHS)

外観
無色～うすい黄色, 澄明の液体
溶解性
エタノール及びアセトンに極めて溶けやすく、水に溶けにくい。
用途
有機合成原料。
化学的特性
Methyl pyruvate is a clear, light yellow, and flammable liquid.
使用
Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.
定義
ChEBI: Methyl pyruvate is a pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol. It is a pyruvate ester and a methyl ester. It derives from a pyruvic acid.
一般的な説明
Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo.