2-bromo-4-methylpropiophenone

Description

It is usually used as the intermediate and raw material in the fine chemistry industry. Specifically, this chemical can act as the intermediate in the synthesis of 4-methyl methcathinone HCl, which is used as the sample for development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials.¹ Moreover, this compound may function as an effective ingredient to prepare the therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives.² In addition, this substance has been demonstrated to be involved in the preparation of a pharmaceutical composition comprising a pyrrole derivative, which shows a desirable activity for the treatment pollakiuria or urinary incontinence.³

Uses

2-Bromo-4'-methylpropiophenone (cas# 1451-82-7) is a compound useful in organic synthesis.

Reference

1. Philp, M.; Shimmon, R.; Stojanovska, N.; Tahtouh, M.; Fu, S. L., Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials. Anal. Methods 2013, 5, 5402-5410.
2. Alexander Wick; Jonathan Frost; Bernard Gaudilliere; Jean Bertin; Regis Dupont; Rousseau, J., Therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives. US Patent 4690931 1987.
3. Masami Tsuda; Mitsushi Tanaka; Nakamura, A., Pyrrole derivatives and medicinal composition. US Patent 5998459 1999.

Chemical Properties

Off-White Solid

Uses

It employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field. Also used as intermediate for 4-methylmethcathinone.