Uses
Grain protectant, insecticide, acaricide.
Uses
trans-Methacrifos is used as a pesticide used to protect crops and vegetation.
Definition
ChEBI: Methacrifos is an organic thiophosphate.
Metabolism
Methacrifos administered in animals is
rapidly metabolized and excreted. The carboxy methyl
ester bond is cleaved as well as the phosphoryl methyl and
vinyl ester bonds. Oxidative desulfuration also occurs.
Toxicity evaluation
The acute oral LD
50 for rats is
678 mg/kg. Inhalation LC50 (4 h) for rats is 2.2 mg/L
air. NOEL (2 yr) for rats is 0.6 mg/kg b.w. daily. ADI
is 6 μg/kg b.w.
