1-myristoyl-2-stearoylphosphatidylcholine

Description

MSPC; PC(14:0/18:0), also knowns as 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers.

Uses

MSPC is used in the macrophage-mediated delivery of multifunctional nanotherapeutics for synergistic chemo-photothermal therapy of solid tumors.

Definition

ChEBI: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 32:0 in which the acyl group specified at positions 1 and 2 are myristoyl and stearoyl respectively. It is a phosphatidylcholine 32:0 and a tetradecanoate ester. It is functionally related to an octadecanoic acid.