CETEARYL ALCOHOL Struktur

CETEARYL ALCOHOL

Bezeichnung:CETEARYL ALCOHOL

CAS-Nr8005-44-5

Englisch Name:CETEARYL ALCOHOL

CBNumberCB9296156

SummenformelC16H34O

Molgewicht242.440002441406

MOL-Datei8005-44-5.mol

CETEARYL ALCOHOL physikalisch-chemischer Eigenschaften

Löslichkeit	Soluble in ethanol (95%), ether, and oil; practically insoluble in water.
InChI	InChI=1S/C18H38O.C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h19H,2-18H2,1H3;17H,2-16H2,1H3
InChIKey	UBHWBODXJBSFLH-UHFFFAOYSA-N
SMILES	C(O)CCCCCCCCCCCCCCC.C(O)CCCCCCCCCCCCCCCCC
CAS Datenbank	8005-44-5(CAS DataBase Reference)

CETEARYL ALCOHOL Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Cetostearyl alcohol occurs as white or cream-colored unctuous masses, flakes, pellets or granules. It has a faint, characteristic sweet odor. On heating, cetostearyl alcohol melts to a clear, colorless or pale yellow-colored liquid free of suspended matter.
Vorbereitung Methode
Cetostearyl alcohol is prepared by the reduction of the appropriate fatty acids from vegetable and animal sources. Cetostearyl alcohol can also be prepared directly from hydrocarbon sources.
Pharmazeutische Anwendungen
Cetostearyl alcohol is used in cosmetics and topical pharmaceutical preparations. In topical pharmaceutical formulations, cetostearyl alcohol will increase the viscosity and act as an emulsifier in both water-in-oil and oil-in-water emulsions. Cetostearyl alcohol will stablize an emulsion and also act as a co-emulsifier, thus decreasing the total amount of surfactant required to form a stable emulsion. Cetostearyl alcohol is also used in the preparation of nonaqueous creams and sticks, and in nonlathering shaving creams. Research articles have been published in which cetostearyl alcohol has been used to control or slow the dissolution rate of tablets or microspheres containing water-soluble drugs, or poorly watersoluble drugs, as well as to stabilize amorphous systems. In combination with other surfactants, cetostearyl alcohol forms emulsions with very complex microstructures. These microstructures can include liquid crystals, lamellar structures, and gel phases.
Sicherheit(Safety)
Cetostearyl alcohol is mainly used in topical pharmaceutical formulations and topical cosmetic formulations.
Cetostearyl alcohol is generally regarded as a nontoxic material. Although it is essentially nonirritating, sensitization reactions to cetostearyl, cetyl, and stearyl alcohols have been reported.
Gamma radiation has been shown to be feasible for sterilization of petrolatum containing cetostearyl alcohol resulting in low levels of radiolysis products, which are of low toxicity.
Lager
Cetostearyl alcohol is stable under normal storage conditions. Cetostearyl alcohol should be stored in a well-closed container in a cool, dry place.
Inkompatibilitäten
Incompatible with strong oxidizing agents and metal salts.
Regulatory Status
Accepted as an indirect food additive and as an adhesive and a component of packaging coatings in the USA. Included in the FDA Inactive Ingredients Database (oral tablets; topical emulsions, lotions, ointments; vaginal suppositories). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

CETEARYL ALCOHOL Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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