Arginin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P337+P313：Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

  P403：An einem gut belüfteten Ort aufbewahren.

L(+)-Arginine Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36:Reizt die Augen.
  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

• S-Sätze Betriebsanweisung:

  S24/25:Berührung mit den Augen und der Haut vermeiden.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

• Chemische Eigenschaften

  Arginine is a diaminomonocarboxylic acid. The nonessential amino acid, arginine, is a urea cycle amino acid and a precursor for the neurotransmitter nitric oxide, which plays a role in the regulation of the brain’s system of dilation and constriction of small blood vessels. It is strongly alkaline and its water solutions absorb carbon dioxide from the air (FCC, 1996). Functionality in foods includes, but is not limited to, nutrient and dietary supplement

• Chemische Eigenschaften

  White crystalline powder

• Physikalische Eigenschaften

  Solubility 14.87 (20 ℃) g/100 g H2O, pI 10.76, dissociation constants: pK1 2.01, pK2 9.04 (a-NH2), pK3 12.48 (guanidyl).
  

• Occurrence

  Reported present in cheese, chocolate, eggs, meat, nuts and other products.

• Verwenden

  Amino acid; nutrient.

• Verwenden

  L-Arginine has been used:
  
  • as a Roswell park memorial institute medium (RPMI) media component in the isolation and culture of peripheral blood mononuclear cells (PBMCs)
  • as a RPMI media component for tissue culture
  • in DMEM medium for the identification and quantification of phosphorylation sites by stable isotope labeling by amino acids in cell culture (SILAC) and LCMS/MS
  
  

• Verwenden

  L-Arginine is used for heart and blood vessel conditions which includes congestive heart failure (CHF), chest pain, high blood pressure and coronary artery disease. It plays a vital role in the treatment of cardiovascular disease due to it being antiatherogenic, anti-ischemic, antiplatelet and antithrombotic. It acts as a growth stimulant and is involved in the treatment of erectile dysfunction in men. It is an important ingredient of tooth paste which provides effective relief for sensitive teeth.

• Definition

  ChEBI: An L-alpha-amino acid that is the L-isomer of arginine.

• Aroma threshold values

  Detection at 100%, faint.

• Taste threshold values

  Taste characteristics at 1000 ppm: hint of sourness.

• Allgemeine Beschreibung

  L-Arginine is an amino acid that plays a key role in many physiological processes such as tissue repair and reproduction. It is a key precursor for synthesizing nitric oxide in mammals. Due to these factors, the dietary supplementation with L-arginine may show a range of health benefits.

• Biochem/physiol Actions

  Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

• Nebenwirkungen

  Nausea, abdominal pain and diarrhea
  Bloating
  Gout
  Headache
  Allergic response
  Airway inflammation or worsening of asthma symptoms

• Sicherheitsprofil

  Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

• Synthese

  Enzymatically, arginine is formed in two reactions from citrulline. The first reaction (citrulline + succinate) is catalyzed by the enzyme arginosuccinate synthetase. It is ATP dependent and with the formation of a new C–N bond in the gaunidino group of arginosuccinate, water is removed and ATP is hydrolyzed. The second reaction is catalyzed by arginine synthetase and involves the scission of arginosuccinate with the formation of arginine and fumaric acid.

• target

  NO | IL Receptor | cGMP

• Arzneimittelwechselwirkung

  L-arginine may interact with certain medications, including :
  Blood-pressure-lowering medications: enalapril (Vasotec), losartan (Cozaar), amlodipine (Norvasc), furosemide (Lasix), etc.
  Erectile dysfunction medications: sildenafil citrate (Viagra), tadalafil (Cialis), etc.
  Blood-thinning medications: clopidogrel (Plavix), enoxaparin (Lovenox), heparin, warfarin (Coumadin), etc.
  Antidiabetic medications: insulin, pioglitazone (Actos), glipizide (Glucotrol), etc.
  Medications that increase blood flow: nitroglycerin (Nitro-Dur, Nitro-Bid, Nitrostat), isosorbide ( Sorbitrate, Imdur, Isordil), etc.
  Diuretic medications: amiloride (Midamor), and triamterene (Dyrenium), spironolactone (Aldactone), etc.

• läuterung methode

  S-Arginine crystallises from H2O as the dihydrate and as plates from EtOH. It also crystallises from 66% EtOH. Its solubility in H2O is 15% at 21o. Its isoelectric point is at pH 10.76. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 817.]

L(+)-Arginine Upstream-Materialien And Downstream Produkte

Arginin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(1186)Suppliers

74-79-3, L(+)-Arginine Verwandte Suche: