Nefazodone

Nefazodone Chemische Eigenschaften,Einsatz,Produktion Methoden

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Chemische Eigenschaften

  Crystalline Solid

• Originator

  Dutonin,Bristol-Myers Squibb,USA

• Verwenden

  A selective serotonin 5-HT2 receptor antagonist. An antidepressant

• Definition

  ChEBI: Nefazodone is a N-arylpiperazine, a N-alkylpiperazine, a member of triazoles, a member of monochlorobenzenes and an aromatic ether. It has a role as an antidepressant, a serotonergic antagonist, a serotonin uptake inhibitor, an alpha-adrenergic antagonist and an analgesic.

• Trademarks

  Serzone (Bristol-Myers Squibb).

• Therapeutic Function

  Antidepressant

• Biologische Funktion

  Although nefazodone (Serzone) is structurally related to trazodone, it is less sedating. It does not block α₁- adrenoreceptors, and its use is not associated with priapism. Nefazodone inhibits the neuronal reuptake of serotonin and blocks 5HT2A receptors. Its short half-life requires dosing twice a day. Nefazodone is not associated with weight gain or sexual dysfunction. It inhibits the cytochrome P450 3A4 isoenzyme that is responsible for 50% of known oxidative metabolism, and therefore, nefazodone can elevate levels of drugs dependent on this pathway for metabolism.

Nefazodone Upstream-Materialien And Downstream Produkte

Nefazodone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(60)Suppliers

83366-66-9, Nefazodone Verwandte Suche: