2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether

Bezeichnung:2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether

CAS-Nr51-03-6

Englisch Name:Piperonyl butoxide

CBNumberCB4337573

SummenformelC19H30O5

Molgewicht338.44

MOL-Datei51-03-6.mol

Synonyma

2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether

2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether physikalisch-chemischer Eigenschaften

Schmelzpunkt	<25 °C
Siedepunkt	180 °C
Dichte	1.059 g/mL at 25 °C(lit.)
Dampfdruck	0.02 hPa (60 °C)
Brechungsindex	n20/D 1.498(lit.)
Flammpunkt	>230 °F
storage temp.	2-8°C
Löslichkeit	water: slightly soluble0.0289g/L at 20.4°C
Aggregatzustand	Liquid
Farbe	Clear yellow
Wichte	1.060 (20/4℃)
Geruch (Odor)	mild odor or odorless
Wasserlöslichkeit	<0.1 g/100 mL at 18 ºC
Merck	14,7476
BRN	288063
Stabilität	Stable. Combustible. Incompatible with oxidizing agents.
InChIKey	HHZWGSFIZRNPFB-UHFFFAOYSA-N
LogP	4.750
CAS Datenbank	51-03-6(CAS DataBase Reference)
IARC	3 (Vol. 30, Sup 7) 1987
NIST chemische Informationen	Piperonyl butoxide(51-03-6)
EPA chemische Informationen	Piperonyl butoxide (51-03-6)

Sicherheit

Kennzeichnung gefährlicher	N,T
R-Sätze:	50/53-51/53-24
S-Sätze:	60-61-45-36/37/39-28A
RIDADR	UN 3082 9/PG 3
WGK Germany	3
RTECS-Nr.	XS8050000
TSCA	Yes
HazardClass	6.1(b)
PackingGroup	III
HS Code	29329990
Giftige Stoffe Daten	51-03-6(Hazardous Substances Data)
Toxizität	LD50 orally in female, male rats: 6150, 7500 mg/kg (Gaines)

Gefahreninformationscode (GHS)

Piperonyl butoxide Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
öLIGE, GELBE BIS BRAUNE FLüSSIGKEIT.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation des Aerosols und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
LECKAGE
Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Umwelt gelangen lassen.
R-Sätze Betriebsanweisung:
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R24:Giftig bei Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Piperonyl butoxide (PBO) is a water insoluble colorless to pale yellow liquid that was developed in the 1940s to increase the effectiveness of various pesticides. It is currently registered as an active ingredient in more than 1500 products used for indoor or outdoor pesticides, including agricultural maintenance of some food crops.
Chemische Eigenschaften
Piperonyl butoxide (PB) is a Light Yellow Liquid. It has no smell or a faint smell and a slightly bitter taste. It does not dissolve in water but can be dissolved in mineral oil and most organic solvents. It is stable to light, resistant to hydrolysis, and is not corrosive. In terms of toxicity, the LD50 (lethal dose for 50% of a test population) is 7500mg/kg in rats when administered orally.
Verwenden
Piperonyl butoxide is used as a synergist for pyrethrins and their synthetic analogues. It is typically added to carbamate, pyrethrin, pyrethroid, and rotenone pesticides to greatly enhance their potency. PBO alone does not have pesticidal properties.
synthetische
First, safrole is obtained from allyl chloride and methylenedioxybenzene. Then, piperonyl butoxide is produced by catalytic hydrogenation, chloromethylation, and etherification reactions.
Definition
ChEBI: Piperonyl butoxide is a member of benzodioxoles. It has a role as a pesticide synergist.
Allgemeine Beschreibung
Pale yellow to light brown liquid with a mild odor and a faint bitter taste.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Piperonyl butoxide can react with oxidizing materials.
Brandgefahr
Piperonyl butoxide is combustible.
Landwirtschaftliche Anwendung
Insecticide synergist: A U.S. EPA restricted Use Pesticide (RUP). Not listed for use in EU countries. Piperonyl butoxide is a synergist, i.e., not a pesticide itself, but enhances the properties of other chemicals. It is used with other pesticides such as pyrethrins, pyrethroids, rotenone and carbamates in food and non-food agricultural products, home and garden products, termite and mosquito products, and veterinary pesticide products. It inhibits the insect’s ability to break down an insecticide before it takes effect, thereby prolonging the action, and reduces the necessity for using a stronger formulation.
Handelsname
Trade names have included Butoxide, Butacide, Butocide, and Pyrenone (mixture with allethrin).
Sicherheitsprofil
Poison by skin contact. Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Many glycol ether compounds have dangerous human reproductive effects, Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomDosition it emits PLATINOL 0 cis-PLATlNUM(II) DIAMMINE- DICHLORIDE
Environmental Fate
PBO is rapidly degraded (half-life 8 h) in the environment by photolysis and is metabolized by soil microorganisms. Its estimated atmospheric half-life is approximately 3 h.
Stoffwechselwegen
Piperonyl butoxide is used primarily in admixture with pyrethrins and some of the pyrethroids to enhance and prolong their insecticidal action. Much of this use is in domestic and industrial situations. Metabolism studies were conducted soon after its discovery and first use in the 1950s and 1960s. The main impetus initially was to understand the mode of action as a synergist. When this was shown to be due to the inhibition of oxidative metabolism, further studies were conducted to address possible toxic interactions with other pesticides and drugs in man.
Piperonyl butoxide undergoes rapid photodegradation and microbial degradation in soil. It is also rapidly metabolised in insects and mammals by oxidative attack at the methylenedioxy carbon atom and in the side chain. A comprehensive review by Casida (1970) describes the chemistry, mode of action and metabolism of piperonyl butoxide and several related methylenedioxyphenyl compounds. Though published nearly 30 years ago, the review remains a very useful compilation of a large amount of information, supported by more than 300 references.
Degradation
Piperonyl butoxide is stable to hydrolysis at pH 5,7 and 9 in sterile buffers in the dark at 25 °C. It is rapidly degraded in aqueous solution at pH 7 in sunlight with a DT₅₀ of 8.4 hours (PM). The compound was found to be relatively stable under a variety of irradiation conditions as a thin film on glass or in organic solvent (methanol, benzene and cyclohexane). Loss of the butoxyethoxy side chain was observed to give 5-methyl-6-propyl-l,3- benzodioxole (2), butoxyethanol (3) and ethanediol (4) (Fishbein and Gaibel, 1970). These studies did not utilise radiolabelled compound. The partial pathways are shown in Scheme 1.
Toxicity evaluation
Piperonyl butoxide has low to very low toxicity in birds.Researchers consider piperonyl butoxide moderately toxic to fish，although it is unlikely to accumulate.Some aquatic invertebrates may be highly sensitive to this compound.
As a synergist, PBO inhibits mixed-function oxidases, including cytochrome P450, and resistance-associated esterases that allow insects to degrade an insecticide, allowing enhanced insecticide efficacy. It does not effectively act as a synergist in mammals.

Piperonyl butoxide Upstream-Materialien And Downstream Produkte

2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

51-03-6, Piperonyl butoxide Verwandte Suche:

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