Methyl indole-4-carboxylate Struktur

Methyl indole-4-carboxylate

Bezeichnung:Methyl indole-4-carboxylate

Englisch Name:Methyl indole-4-carboxylate

CBNumberCB3773657

SummenformelC10H9NO2

Molgewicht175.18

Methyl indole-4-carboxylate physikalisch-chemischer Eigenschaften

Schmelzpunkt	68-71 °C(lit.)
Siedepunkt	306.47°C (rough estimate)
Dichte	1.1999 (rough estimate)
Brechungsindex	1.5060 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	soluble in Methanol
pka	15.80±0.30(Predicted)
Aggregatzustand	Crystalline Powder
Farbe	Off-white to green
BRN	141826
InChIKey	WEAXQUBYRSEBJD-UHFFFAOYSA-N
CAS Datenbank	39830-66-5(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
off-white to green crystalline powder
Verwenden
- Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells
- Reactant for preparation of inhibitor for β-tryptase
- Reactant for preparation of histamine H3 antagonists
- Reactant for preparation of JNK3 MAP kinase inhibitors
- Reactant for preparation of nucleosides
Verwenden
• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• ;Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells2• ;Reactant for preparation of inhibitor for β-tryptase3• ;Reactant for preparation of histamine H3 antagonists4• ;Reactant for preparation of JNK3 MAP kinase inhibitors5• ;Reactant for preparation of nucleosides6
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 1405, 1989 DOI: 10.1002/jhet.5570260533
Chemical and Pharmaceutical Bulletin, 29, p. 249, 1981 DOI: 10.1248/cpb.29.249
Allgemeine Beschreibung
The IR and UV spectra of methyl indole-4-carboxylate was studied.