25535-16-4
基本信息
碘化酶
3,8-DIAMINO-5-(3-DIETHYL-AMINOPROPYL)-6-PHENYLPHENANTHRIDIUM IODIDE METHIODIDE
3,8-DIAMINO-5-(3-[DIETHYLMETHYLAMMONIO])-6-PHENYLPHENAN-THRIDINIUM DIIODIDE
3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM
3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM DIIODIDE
PHENANTHRIDINIUM, 3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYL-, DIIODIDE
PI
PROPIDIUM IODIDE
3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-phenanthridiniudii
3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridiniumdiiod
3,8-diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridiniumiodidemethiodi
Propidium iodide solution
Propidium diiodide
PROPIDIUM IODIDE 95-98%
PROPIDIUM IODIDE, FOR FLUORESCENCE
PROPIDIUM IODIDE 95%
-Cellstain-PiSolution
-Cellstain-Pi
PROPIDIUM IODIDE RED POWDER
3,8-Diamino-5-[3-(diethylmethylamino)propyl]-6-phenylphenanthridium,diiodide
物理化学性质
| 熔点 | 220-225 °C (dec.) (lit.) |
| 熔点 | 220-225 °C (dec.)(lit.) |
| 密度 | 1.5072 (estimate) |
| 储存条件 | 2-8°C |
| 储存条件 | 2-8°C |
| 溶解度 | 难溶于水 |
| 形态 | 片状粉末 |
| 颜色 | 深红 |
| 水溶解性 | Soluble in water at 1mg/ml |
| 敏感性 | Light Sensitive & Hygroscopic |
| 最大波长(λmax) | 493 nm, 535 nm |
| BRN | 3843838 |
| 生物领域应用 | Detecting nucleic acids,cancer cells,spores,activity of hydrolase,microorganisms; apoptosis assay; measuring beta-amyloid in Alzheimer’s disease (AD); treating diseases associated with androgens,cancer |
| 主要应用 | Electroluminescent displays; photoresists |
| CAS 数据库 | 25535-16-4(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS08 |
| 警示词 | 警告 |
| 危险性描述 | H341 |
| 防范说明 | P201-P202-P280-P308+P313-P405-P501 |
| 危险品标志 | Xi,Xn |
| 危险品标志 | Xi |
| 危险类别码 | 36/37/38-68-67-48/20/22-40-36/38-22-20-63 |
| 危险类别码 | R36/37/38 |
| 安全说明 | 26-36-22-36/37 |
| 安全说明 | S26 |
| WGK Germany | 3 |
| WGK Germany | 3 |
| RTECS号 | SF7949600 |
| F | 3-8-10-23 |
| 海关编码 | 29339900 |
应用领域
常见问题列表
碘化丙啶是一种可对DNA染色的细胞核染色试剂，常用于细胞凋亡检测，英文全称是Propidium Iodide。它是一种溴化乙啶的类似物，在嵌入双链DNA后释放红色荧光。
Propidium Iodide is a cell-membrane impermeable dye with characteristic excitation maximum at 535 nm and emission maximum at 617 nm which intercalates with nucleic acids with a stoichiometry of one dye per 4-5 base pairs with little sequence preference. Propidium Iodide has evidenced of having no toxic effects on neurons, being today’s most common marker for membrane integrity and cell viability when applied prior to fixation (pre-fixation Propidium Iodide staining method). The pre-fixation staining has been widely used for quantitative assessments of neuronal cell decline in models of acute neurodegeneration, visualized as intensely labeled PI + -pycnotic nuclei of degenerating neurons . Propidium Iodide cannot cross the membrane of live cells, making it useful to measure the percentage of apoptotic cells by flow-cytometric analysis. The flow cytometric data shows an excellent correlation with the results obtained with both electrophoretic and colorimetric methods. This new rapid, simple and reproducible method proves useful for assessing apoptosis of specific cell populations in heterogeneous tissues such as bone marrow, thymus and lymph nodes.